FIG. 1.

(A) Schematic representation of the genome organization of the chimeric YF/DEN virus. The DEN-2 prM and E genes are indicated by a cross-hatched bar, and YFV-17D genes are indicated by open bars. (B) Expression of DEN-2 prM and E genes. SW-13 cells were infected with YFV-17D or with the chimeric YF/DEN virus and were metabolically labeled at 16 h postinfection. The radiolabeled proteins were immunoprecipitated and analyzed on a 12% polyacrylamide gel. Positions of radiolabeled molecular size markers (in kilodaltons) are on the right.