FIG. 2.

PrM- and E-specific and E331-epitope-specific CD8 T-cell responses in YF/DEN virus-immunized mice. Mice were immunized by s.c. inoculation with 5 × 10⁵ PFU of YF/DEN virus or YFV-17D or were mock immunized with PBS, and the frequencies of prM- and E-specific CD8 T cells were measured 14 days postimmunization by intracellular IFN-γ staining. The frequencies of specific cells are shown as percentages of total CD8 T cells. The results shown are from individual mice and differ slightly from the average frequencies presented in the text. vv, vaccinia virus.