Table 1.
Characteristics of cohort
| Characteristic | Overall | Parathyroidectomy | Nonsurgical |
|---|---|---|---|
| Age, median (IQR) | 65.00 (56.00-73.00) | 62.00 (54.00-70.00) | 66.00 (57.00-74.00) |
| Age, y | |||
| ≤ 50 | 7284 (14.3%) | 2354 (17.4%) | 4930 (13.2%) |
| 51-65 | 18 650 (36.6%) | 5867 (43.4%) | 12 783 (34.1%) |
| 66-75 | 15 522 (30.5%) | 3916 (29.0%) | 11 606 (31.0%) |
| >75 | 9502 (18.6%) | 1369 (10.1%) | 8133 (21.7%) |
| Gender | |||
| Female | 37 713 (74.0%) | 10 390 (76.9%) | 27 323 (73.0%) |
| Male | 11 793 (23.1%) | 2902 (21.5%) | 8891 (23.7%) |
| Race/ethnicity | |||
| Race—Black or African American | 9277 (18.2%) | 1781 (13.2%) | 7496 (20.0%) |
| Race—White | 34 085 (66.9%) | 9775 (72.4%) | 24 310 (64.9%) |
| Race—Asian, American Indian, Pacific Islander, Other/unknown | 7596 (14.9%) | 1950 (14.4%) | 5646 (15.1%) |
| Ethnicity—Hispanic or Latino | 2016 (4.0%) | 601 (4.4%) | 1415 (3.8%) |
| Region | |||
| South | 16 365 (32.1%) | 3867 (28.6%) | 12 498 (33.4%) |
| West | 5842 (11.5%) | 1880 (13.9%) | 3962 (10.6%) |
| Midwest | 12 910 (25.3%) | 3895 (28.8%) | 9015 (24.1%) |
| Northeast | 15 841 (31.1%) | 3864 (28.6%) | 11 977 (32.0%) |
| Anthropometrics | |||
| Weight, kg: median (IQR) | 79.80 (66.68-95.10) | 81.01 (68.04-96.03) | 79.30 (66.22-94.62) |
| Height, cm: median (IQR) | 165.10 (158.75-170.99) | 165.10 (160.00-171.50) | 165.10 (157.78-170.20) |
| BMI: median (IQR) | 29.00 (25.00-33.78) | 29.20 (25.30-33.98) | 28.89 (24.89-33.69) |
| Bone density diagnoses | |||
| Osteopenia | 3904 (7.7%) | 1511 (11.2%) | 2393 (6.4%) |
| Osteoporosis | 7475 (14.7%) | 2747 (20.3%) | 4728 (12.6%) |
| Complications of PHPT at time of diagnosis | |||
| Fracture history at PHPT diagnosis | 1300 (2.55%) | 279 (2.07%) | 1021 (2.73%) |
| Nephrolithiasis history at PHPT diagnosis | 4796 (9.41%) | 1640 (12.14%) | 3156 (8.43%) |
| Stage 3 CKD history at PHPT diagnosis | 7537 (14.79%) | 1091 (8.08%) | 6446 (17.21%) |
Abbreviations: BMI, body mass index; CKD, chronic kidney disease; IQR, interquartile range; PHPT, primary hyperparathyroidism.