Fig. 3.
Hif-2afl mice show no resistance to MCMV, another dsDNA virus. BMDMs from naïve Hif-1afl and Hif-2afl mice were cultivated for 7 days. BMDMs were infected with 106 PFU of MCMV in vitro and subjected to mRNA analysis at 2 dpi (data are given as n-fold induction of MCMV gB mRNA over mRNA of ribosomal protein 16S (Rsp16); C denotes are untreated control cells. Results are mean±s.e.m. The numbers in the graphs indicate the number of animals tested. ns, not statistically significant (two-tailed unpaired t-test).