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. 2024 May 7;11(26):2401617. doi: 10.1002/advs.202401617

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© 2024 The Authors. Advanced Science published by Wiley‐VCH GmbH

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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a) Schematic illustration of the tetrahedral structure loaded with AS1411 in order to release siRNA in malignant melanoma. Reproduced with permission from.^[ ⁸⁵ ^] Copyright 2021, American Chemical Society. b) (A) Antitumor therapy of TDN‐FA/PL1/Pcsk9 siRNA via nanoplatform separated, delivered the Pcsk9 siRNA in tumor, and decreasing PCSK9‐mediated MHC I degradation. (B) Body weight of mouse. (C) different mice tumors photo. Reproduced with permission from.^[ ⁸⁶ ^] Copyright 2022, American Chemical Society.