Table 1.
Preoperative clinical characteristics of patients, comparison of laparoscopic cholecystectomy and conversion to open cholecystectomy groups
| Total (n = 42) | LC group | COC group | p = value | |
|---|---|---|---|---|
| (n = 28, 66.6%) | (n = 14, 33.3%) | |||
| Age, median (range), year | 68 (55–85) | 71.50 (55–85) | 68 (59–83) | 0.218* |
| Sex, F:M, n | 16:26 | 14:14 | 2:12 | 0.025** |
| History of calculi before perforation, n (%) | 18 (42.9%) | 13 (46.4%) | 5 (35.7%) | 0.508** |
| Modes of diagnosis, n (%) | 0.161** | |||
| US | 16 (38.1%) | 12 (42.9%) | 4 (28.6%) | |
| CT | 22 (52.4%) | 15 (53.6%) | 7 (50.0%) | |
| MRI | 4 (9.5%) | 1 (3.6%) | 3 (21.4%) | |
| Wall thickness, median, milimeter | 14 (7–16) | 14 (8–16) | 13 (7–14) | 0.681* |
| Presenting complaint, n (%) | ||||
| Abdominal pain | 34 (80.95%) | 24 (85.7%) | 10 (71.4%) | 0.266** |
| Vomiting | 18 (42,85%) | 11 (39.3%) | 7 (50.0%) | 0.508** |
| Fever | 16 (38.09%) | 12 (42.9%) | 4 (28.6%) | 0.369** |
| Comorbidities, n (%) | ||||
| Diabetus Mellitus | 18 (42.9%) | 10 (35.71%) | 8 (57.14%) | 0.186** |
| Hypertension | 26 (61.9%) | 17 (60.71%) | 9 (64.28%) | 0.822** |
| Coronary artery disease | 22 (52.4%) | 16 (57.14%) | 6 (42.85%) | 0.382** |
| Cerebrovascular disease | 8 (19.0%) | 5 (17.85%) | 3 (21.42%) | 0.781** |
| Chronic lung disease | 8 (19.0%) | 5 (17.85%) | 3 (21.42%) | 0.781** |
| ASA, n (%) | 0.392** | |||
| I | 1 (2.4%) | 1 (3.6%) | 0 | |
| II | 6 (14.3%) | 3 (10.7%) | 3 (21.4%) | |
| III | 24 57.1%) | 18 (64.3%) | 6 (42.9%) | |
| IV | 11 (26.2%) | 6 (21.4%) | 5 (35.7%) | |
| CCI, median (IQR) | 2 (1–6) | 2 (1–3) | 3 (1–6) | 0.02* |
| Tokyo classification, n (%) | 0.007** | |||
| I | 7 (16.7%) | 6 (21.4%) | 1 (7.1%) | |
| II | 19 (45.2%) | 16 (57.1%) | 3 (21.4%) | |
| III | 16 (38.1%) | 6 (21.4%) | 10 (71.4%) | |
| Preoperative WBC, median (range) | 12300 (8600–28920) | 11900 (9800–24210) | 12300 (8600–28920) | 0.486* |
| Preoperative glucose, median (range) | 146 (111–206) | 153.50 (111–206) | 146.0 (135–176) | 0.789* |
n: number, SD: standard deviation, F: female, M: male, US: Ultrasonography, CT: Computed tomografi, MRI: magnetic resonance imaging, WBC: white blood cell, MODS: Multiple Organ Dysfunction Sydrome, LC: laparoscopic cholecystectomy, COC: conversion to open cholecystectomy, CCI: Charlson comorbidity index, IQR: Interquartile range, ASA: American Society of Anaesthetiologist,†: Clavien – Dindo ≥ III
Bold values indicate statistically significant p values (p < 0.05)
*: Mann -Whitney U test, **: Chi-square test, ***: Fisher’s exact tests