Table 5.
Comparison between the high-quality blastocyst group and the non-high-quality blastocyst group
| Characteristics | Non-high-quality blastocyst group (N = 1800) | High-quality blastocyst group (N = 124) |
P value |
|---|---|---|---|
| Cycle Type | 0.875 | ||
| First Cycle | 732(40.67%) | 49(39.52%) | |
| Repeat Cycle | 1068(59.33%) | 75(60.48%) | |
| Type of infertility | 0.301 | ||
| Primary infertility | 579(32.17%) | 46(37.10%) | |
| Secondary infertility | 1221(67.83%) | 78(62.90%) | |
| Duration of infertility (years) | 5.28 ± 4.51 | 5.06 ± 4.56 | 0.317 |
| Age (years) | 37.87 ± 5.57 | 35.39 ± 4.87 | 6.51E-07 |
| BMI | 22.31 ± 2.87 | 21.54 ± 2.45 | 0.020 |
| Basal FSH (mIU/mL) | 13.35 ± 8.02 | 12.83 ± 7.47 | 0.360 |
| Basal LH (mIU/mL) | 5.28 ± 4.97 | 6.06 ± 8.14 | 0.508 |
| FSH/LH | 3.25 ± 8.03 | 2.93 ± 2.10 | 0.175 |
| Basal P (ng/mL) | 0.89 ± 1.82 | 1.32 ± 2.69 | 0.017 |
| Basal E2 (pg/mL) | 70.47 ± 80.01 | 82.46 ± 130.57 | 0.433 |
| AFC | 2.68 ± 1.03 | 3.03 ± 0.95 | 0.0002 |
| AMH (ng/mL) | 0.47 ± 0.30 | 0.52 ± 0.28 | 0.037 |
| FSH on HCG day (mIU/mL) | 19.19 ± 6.26 | 20.13 ± 5.47 | 0.020 |
| LH on HCG day (mIU/mL) | 3.54 ± 2.76 | 3.11 ± 2.86 | 0.009 |
| P on HCG day (ng/mL) | 0.77 ± 0.65 | 0.80 ± 0.44 | 0.036 |
| E2 on HCG day (pg/mL) | 897.46 ± 593.19 | 1148.06 ± 751.30 | 3.36E-06 |
| Delta FSH | 9.66 ± 6.81 | 10.99 ± 6.55 | 0.006 |
| Delta LH | -0.86 ± 3.17 | -1.02 ± 3.39 | 0.180 |
| Delta P | 0.05 ± 0.87 | 0.07 ± 0.46 | 0.558 |
| Delta E2 | 820.94 ± 599.70 | 1082.54 ± 759.60 | 1.97E-06 |
| Number of follicles ≥ 14 mm on HCG day | 2.14 ± 1.41 | 2.72 ± 1.51 | 7.48E-07 |
| Total dose of Gn (IU) | 1686.66 ± 843.79 | 1740.12 ± 698.21 | 0.136 |
| Dosing days of Gn (day) | 8.27 ± 3.16 | 8.41 ± 2.57 | 0.148 |
| Retrieved oocytes | 1.82 ± 1.27 | 2.47 ± 1.68 | 8.34E-07 |
| MII oocytes | 1.59 ± 1.19 | 2.31 ± 1.56 | 2.56E-09 |
| 2PN fertilized oocytes | 0.90 ± 1.03 | 1.44 ± 1.28 | 3.42E-07 |
| Cleavage embryo | 1.07 ± 1.06 | 2.00 ± 1.21 | 1.40E-19 |
| High-quality cleavage embryo | 0.03 ± 0.36 | 0.27 ± 0.64 | 7.72E-25 |
Continuous variables are expressed as mean ± SD, categorical variables as absolute frequencies, n (%)
BMI, body mass index; FSH, follicular-stimulating hormone; LH, luteinizing hormone; P, progesterone; E2, estradiol; AFC, antral follicle count; AMH, anti-Müllerian hormone; Gn, gonadotropin; HCG, human chorionic gonadotropin