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. 2024 Jun 12;23(3):316–340. doi: 10.2463/mrms.rev.2024-0007

Table 1.

ROIs used for identifying visual white matter pathways using tractography in previous studies

Tract ROIs Reference
ON Optic nerve head (manually placed sphere) and optic chiasm (FreeSurfer segmentation114 on structural image). Miller et al.,2019108; Takemura et al., 2023105
OT Optic chiasm (FreeSurfer segmentation on structural image) and LGN (manually placed sphere on structural image with a guide of deterministic tractography from the optic chiasm). Ogawa et al., 2014118; Takemura et al., 2019119; Ogawa et al., 2022130
Optic chiasm (nonlinear warping from the optic chiasm identified from 5 subjects) and LGN (automated identification from tractography and shape analysis). Kammen et al., 2016120
OR LGN (manually placed sphere with a guide of deterministic tractography from the optic chiasm) and V1 (manually drawn calcarine sulcus). Sherbondy et al., 2008117
LGN (manually drawn based on structural image with a guide of deterministic tractography from the optic chiasm) and V1 (FreeSurfer segmentation on structural image). Ogawa et al., 2014118; Takemura et al., 2019119; Ogawa et al., 2022130
Manually placed NOT ROIs around the medial, anterior, and lateral Mayer’s loop. Chamberland et al., 2017154
LGN (automated identification from tractography and shape analysis) and V1 (Benson atlas).174,175 Kammen et al., 2016120
Thalamus and V1 (FreeSurfer segmentation on structural image) combined with qT1. Schurr et al., 2018157
Thalamus and visual cortex endpoint ROIs and axial waypoint ROIs transformed from the MNI template. Caffarra et al., 2021182
LGN (FreeSurfer-based segmentation) and V1 (Benson atlas).174,175 Lerma-Usabiaga et al., 2023123
Forceps Major Splenium and occipital lobe white matter. Dougherty et al., 2005193
Coronal waypoint ROIs in each hemisphere’s occipital cortex transformed from the MNI space. Yeatman et al., 201257
Splenium the entire coronal section posterior to the splenium Scherf et al., 2014195
VOF Ventral occipitotemporal cortex (FreeSurfer segmentation). In addition, streamlines intermingle with the arcuate fasciculus identified by using the AFQ57 is removed. Yeatman et al., 2014160
Waypoint ROIs in the dorsal and lateral part of the occipital white matter. Takemura et al., 2016207
ROIs used in Yeatman et al., 2014160 and Takemura et al., 2016207 combined with qT1. Schurr et al., 2019217

LGN, lateral geniculate nucleus; ON, optic nerve; OR, optic radiation; OT, optic tract; qT1, quantitative T1; VOF, vertical occipital fasciculus; V1, primary visual cortex.