TABLE 1.

Participant characteristics at baseline (n = 904 unless otherwise specified).

	Median (IQR)
Age, years	40.9 (33.7–48.9)
Disease duration, years	7.6 (3.8–11.7)
Visit number	2 (1–4)
Female, n (%)	688 (76.1)
EDSS score	1.5 (1–2)
PDDS score	0 (0–1)
MDT (dominant hand; n = 870), s	22.5 (20.2–25.5)
MDT (non‐dominant hand; n = 870), s	23.6 (21.2–26.6)
WST (n = 837), s	5.8 (5.0–6.8)
PST (n = 879)	54 (47–60)
MusiQoL index (range 0–100; n = 736)	78.2 (69.4–86.4)
MusiQoL psychological score (range 0–100; n = 736)	80 (65–95)
PSWQ score (range 16–80; n = 725)	40 (27–52)
PHQ score (range 0–27; n = 732)	5 (2–9)

Abbreviations: EDSS, Expanded Disability Status Scale; IQR, interquartile range; MDT, manual dexterity test; MusiQoL, Multiple Sclerosis International Quality of Life questionnaire; PDDS, Patient‐Determined Disease Steps; PHQ, Patient Health Questionnaire; PST, processing speed test; PSWQ, Penn State Worry Questionnaire; WST, walking speed test.

Note: Higher scores on the PSWQ and PHQ are indicative of greater worry and depression, respectively. Lower scores on the MusiQoL index or subscores are indicative of worse quality of life.