TABLE 1.
Hormone and group | Hormone concn (mean ± SE) on day postinoculationb
|
|||||
---|---|---|---|---|---|---|
0 | 10 | 15 | 20 | 30 | 40 | |
Testosterone | ||||||
Intact males | 0.69 ± 0.17* | 0.84 ± 0.17* | 1.13 ± 0.36* | 0.92 ± 0.25* | 0.77 ± 0.19* | 0.70 ± 0.13* |
Castrated males | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 |
T-treated males | 0.00 ± 0.00 | 8.24 ± 0.74*† | 6.28 ± 0.91*† | 6.62 ± 1.18*† | 2.73 ± 0.42*† | 0.71 ± 0.28* |
Estradiol | ||||||
Intact females | 25.8 ± 6.81* | 27.0 ± 5.57* | 20.8 ± 8.39* | 25.9 ± 7.78* | 38.2 ± 10.1* | 55.2 ± 10.2* |
Ovx females | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 |
E2-treated females | 0.00 ± 0.00 | 166.6 ± 20.6*† | 123.1 ± 21.9*† | 87.5 ± 8.9*† | 162.3 ± 18.8*† | 109.7 ± 19.3*† |
Sex steroid hormone concentrations in males and females that either were intact, gonadectomized (i.e., males were castrated and females were ovariectomized [Ovx]), or gonadectomized with sex steroids replaced (i.e., gonadectomized males received testosterone [T]-filled capsules and gonadectomized females received estradiol [E2]-filled capsules).
Testosterone levels are in nanograms per milliliter, and estradiol levels are in picograms per milliliter. An asterisk indicates that intact and hormone-treated animals had higher hormone concentrations than their gonadectomized counterparts on the corresponding day, based on an analysis of variance (P < 0.05). A dagger indicates that hormone-treated animals had higher sex steroid concentrations than their intact counterparts on the corresponding day, based on an analysis of variance (P < 0.05).