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. 2000 Sep;74(17):8213–8217. doi: 10.1128/jvi.74.17.8213-8217.2000

TABLE 1.

Sex steroid hormone concentrationsa

Hormone and group Hormone concn (mean ± SE) on day postinoculationb
0 10 15 20 30 40
Testosterone
 Intact males 0.69 ± 0.17* 0.84 ± 0.17* 1.13 ± 0.36* 0.92 ± 0.25* 0.77 ± 0.19* 0.70 ± 0.13*
 Castrated males 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00
 T-treated males 0.00 ± 0.00 8.24 ± 0.74* 6.28 ± 0.91* 6.62 ± 1.18* 2.73 ± 0.42* 0.71 ± 0.28*
Estradiol
 Intact females 25.8 ± 6.81* 27.0 ± 5.57* 20.8 ± 8.39* 25.9 ± 7.78* 38.2 ± 10.1* 55.2 ± 10.2*
 Ovx females 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00
 E2-treated females 0.00 ± 0.00 166.6 ± 20.6* 123.1 ± 21.9* 87.5 ± 8.9* 162.3 ± 18.8* 109.7 ± 19.3*
a

Sex steroid hormone concentrations in males and females that either were intact, gonadectomized (i.e., males were castrated and females were ovariectomized [Ovx]), or gonadectomized with sex steroids replaced (i.e., gonadectomized males received testosterone [T]-filled capsules and gonadectomized females received estradiol [E2]-filled capsules). 

b

Testosterone levels are in nanograms per milliliter, and estradiol levels are in picograms per milliliter. An asterisk indicates that intact and hormone-treated animals had higher hormone concentrations than their gonadectomized counterparts on the corresponding day, based on an analysis of variance (P < 0.05). A dagger indicates that hormone-treated animals had higher sex steroid concentrations than their intact counterparts on the corresponding day, based on an analysis of variance (P < 0.05).