TABLE 2.
Plasma anti-Seoul virus IgG responsesa
| Group | Anti-Seoul virus IgG response (mean ± SE) on day postinoculationb
|
|||||
|---|---|---|---|---|---|---|
| 0 | 10 | 15 | 20 | 30 | 40 | |
| Intact males | 0.8 ± 0.6 | 4.9 ± 3.0 | 84.0 ± 22.0 | 106.0 ± 19.0* | 332.0 ± 47.0* | 342.1 ± 56.0* |
| Castrated males | 1.0 ± 0.7 | 1.0 ± 1.0 | 82.0 ± 21.0 | 106.0 ± 27.0* | 280.0 ± 71.0* | 387.3 ± 84.0* |
| T-treated males | 1.0 ± 0.7 | 2.0 ± 0.9 | 33.0 ± 10.0 | 108.0 ± 14.0* | 314.0 ± 41.0* | 426.7 ± 43.0* |
| Intact females | 3.0 ± 1.0 | 9.0 ± 4.0 | 36.0 ± 10.0 | 60.0 ± 14.0 | 189.0 ± 55.0 | 219.6 ± 63.0 |
| Ovx females | 2.0 ± 0.8 | 4.0 ± 2.0 | 7.0 ± 3.0 | 54.0 ± 16.0 | 187.0 ± 56.0 | 209.2 ± 53.0 |
| E2-treated females | 3.0 ± 1.0 | 8.0 ± 2.0 | 19.0 ± 6.0 | 39.0 ± 8.0 | 178.0 ± 42.0 | 209.1 ± 39.0 |
a
Plasma anti-Seoul virus IgG responses in males and females that either were intact, gonadectomized (i.e., males were castrated and females were ovariectomized [Ovx]), or gonadectomized with sex steroids replaced (i.e., gonadectomized males received testosterone [T]-filled capsules and gonadectomized females received estradiol [E2]-filled capsules).
b
Data are presented as IgG units, in which the mean OD of each test sample was divided by the OD of the positive control sample run on the same microtiter plate. An asterisk indicates that males had higher IgG responses than females, regardless of hormone manipulation, based on an analysis of variance (P < 0.05).