TABLE 3.
Sample and group | No. of virus-shedding rats/total on day postinoculationb
|
||||
---|---|---|---|---|---|
10 | 15 | 20 | 30 | 40 | |
Saliva samples | |||||
Intact males | 6/11 | 7/10 | 6/11 | 6/11 | 6/11 |
Castrated males | 4/9 | 4/9 | 6/9 | 5/9 | 8/9 |
T-treated males | 9/10 | 7/10 | 4/10 | 6/10 | 7/10 |
Total males | 19/30* | 18/29 | 16/30 | 17/30* | 21/30 |
Intact females | 3/9 | 6/9 | 5/9 | 2/9 | 2/9 |
Ovx females | 4/10 | 7/10 | 2/10 | 2/10 | 6/10 |
E2-treated females | 3/10 | 10/10 | 3/10 | 1/10 | 6/10 |
Total females | 10/29 | 23/29 | 11/29 | 5/29 | 14/29 |
Fecal samples | |||||
Intact males | 5/11 | 4/11 | 4/11 | 5/11 | 1/11 |
Castrated males | 6/9 | 5/9 | 7/9 | 4/8 | 1/9 |
T-treated males | 4/10 | 6/10 | 7/10 | 7/9 | 1/10 |
Total males | 15/30 | 15/30 | 18/30 | 16/29* | 3/30 |
Intact females | 7/9 | 4/9 | 4/9 | 1/8 | 0/9 |
Ovx females | 9/10 | 4/10 | 6/10 | 2/10 | 2/10 |
E2-treated females | 6/9 | 5/10 | 8/10 | 2/10 | 1/10 |
Total females | 22/28 | 13/29 | 18/29 | 5/28 | 3/29 |
Virus shedding in saliva and feces from males and females that either were intact, gonadectomized (i.e., males were castrated and females were ovariectomized [Ovx]), or gonadectomized with sex steroids replaced (i.e., gonadectomized males received testosterone [T]-filled capsules and gonadectomized females received estradiol [E2]-filled capsules).
An asterisk indicates that more males shed virus than females on the respective day postinoculation, based on chi-square analyses (P < 0.05).