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. 2023 Oct 30;2(4):e20230029. doi: 10.1002/SMMD.20230029

FIGURE 1.

FIGURE 1

Chemical modifications of HA. (A) Esterification reaction on hydroxyl groups. Reproduced with permission. 17 Copyright 2021, American Chemical Society. (B) Oxidation reaction on hydroxyl groups. Reproduced with permission. 18 Copyright 2017, Elsevier. (C) Amidation rection on carboxyl groups by carbodiimide chemistry. Reproduced with permission. 19 Copyright 2016, Elsevier. (D) Deacetylation of HA on the N‐acetyl group. Reproduced with permission. 20 Copyright 2020, Elsevier.