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. 2024 Jan 8;31(4):e16192. doi: 10.1111/ene.16192

FIGURE 2.

FIGURE 2

Comparing intraepidermal nerve fiber density between patients and healthy controls. Intraepidermal nerve fiber density (fibers/mm). Horizontal lines indicate the mean and the bars the standard deviation (SD) of patients and healthy controls. Patients have significantly fewer fibers/mm at both the proximal (p = 0.014) and distal (p < 0.01) biopsy sites compared to controls. The number of proximal skin biopsies of HCs was smaller (n = 13) because not all consented to a second skin biopsy. HC, healthy controls; IENFD, intraepidermal nerve fiber density; SFN, small fiber neuropathy.