FIGURE 3.

Defining small fiber polyneuropathy patients according to the NEURODIAB criteria. Diagnosis of definite SFN based on NEURODIAB criteria. All 30 patients fulfilled the criteria for definite SFN, 17 of whom had both pathological IENFD and abnormal quantitative sensory testing (QST) thermal thresholds at the foot, two had only pathological thermal threshold abnormalities and 11 had only pathological IENFD. All patients had clinical evidence of small fiber damage and normal sural nerve conduction studies. IENFD, intraepidermal nerve fiber density; SFN, small fiber neuropathy.