. 2024 Feb 2;31(4):e16186. doi: 10.1111/ene.16186

TABLE 2.

Patient characteristics with initial magnetic resonance imaging findings, cumulative treatment, disease duration at time of baseline testing, individual test results and disease activity 1 year prior to and at the moment of baseline and follow‐up testing.

Patient ID ^a	Sex/age at baseline testing	Years of education	Year of diagnosis	Disease duration at baseline testing, years	Initial MRI findings	Cumulative treatment	Abnormal neuropsychological test results ^b		Disease activity
Patient ID ^a	Sex/age at baseline testing	Years of education	Year of diagnosis	Disease duration at baseline testing, years	Initial MRI findings	Cumulative treatment	Baseline	Follow‐up	1 year prior to baseline testing	At moment of baseline testing	1 year prior to follow‐up testing	At moment of follow‐up testing
1	F/50	15	2005, definite	15	CC, ST, GM, IT, DR	C, PLEX, MMF	Phonological fluency	Cognitive flexibility, mathematics	Inactive	Inactive	Inactive	Inactive
2	M/38	15	2016, probable	4	CC, ST, IT, DR, LM, CE	C, PLEX, AZA, RTX, MMF	Information processing speed, phonological fluency	Information processing speed, cognitive flexibility, phonological fluency	Inactive	Inactive	Inactive	Inactive
4	M/39	15	2018, definite	2	CC, ST, GM, IT, DR, LM, CE	CYC, NAT	Phonological fluency	Phonological fluency	01/2020: Disease activity with migraine	Active	Inactive	Inactive
6	F/43	17	2011, definite	9	CC, ST, IT, DR	C, PLEX, MMF, AZA	Information processing speed, cognitive flexibility, mathematics, visual perception, semantic and phonological fluency	Missing data	Inactive	Inactive	/	/
7	M/70	15	2018, definite	2	CC, ST, GM, IT, DR	C, PLEX, MMF, RTX	Information processing speed, verbal memory, visual perception, neglect, phonological fluency, finger dexterity	Information processing speed, cognitive flexibility, verbal memory, wordfinding, finger dexterity	Inactive	Inactive	Inactive	Inactive
8	F/32	14	2016, definite	4	CC, ST	RTX	Mathematics, phonological fluency	Phonological fluency	10/2020: Disease activity with BRAO lesions	Active	Inactive	Inactive
10	F/30	17	2015, definite	5	CC, ST, DR	C, MMF, IVIG, RTX	No cognitive impairment	No cognitive impairment	Inactive	Inactive	01/2021: disease activity with sensory complaints	Inactive
11	F/34	12	2019, probable	2	CC, ST	None	Mathematics, semantic fluency, phonological fluency, finger dexterity	Semantic fluency, phonological fluency, verbal reasoning	2020: disease activity with sensory complaints, migraine and visual symptoms	Inactive	Inactive	Inactive
13	F/35	15	2020, definite	5	CC, ST, DR	C, PLEX, RTX, MMF	Verbal attention, mathematics	Cognitive flexibility, mathematics, verbal memory	Inactive	Inactive	Inactive	Inactive
14	F/31	16	2019, definite	2	CC, ST	C	Cognitive flexibility	Missing data	Inactive	Inactive	/	/
15	M/45	17	2020, definite	1	CC, ST, IT, DR	C, PLEX, MMF, RTX	No cognitive impairment	No cognitive impairment	Inactive	Inactive	Inactive	Inactive
16	F/38	15	2020, probable	1	CC, ST	PLEX, MMF	Phonological fluency	No cognitive impairment	Active	Active	Inactive	Inactive
17	M/28	15	2020, probable	1	CC, ST, IT, DR, LM	C, PLEX, RTX, MMF	Information processing speed, visual perception, phonological fluency, wordfinding	Cognitive flexibility	09/2020: disease activity with visual symptoms	Active	Inactive	Inactive

Abbreviations: AZA, azathioprine; BRAO, Branch Retinal Artery Occlusion; C, corticosteroids; CC, corpus callosum; CE, contrast enhancing; CYC, cyclophosphamide; DR, diffusion restrictive; F, female; GM, grey matter; IT, infratentorial; IVIG, intravenous immunoglobulin; LM, leptomeningeal; M, male; MMF, mycophenolate mofetil; MRI, magnetic resonance imaging; NAT, natalizumab; NP, not performed; PLEX, plasma exchange; RTX, rituximab; ST, supratentorial.

^{^a}

The same patient ID is used as in Dekeyser et al. [28]. For a more comprehensive overview we refer to this article.

^{^b}

Deficits on neuropsychological tests are shown.