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. 2022 Dec 16;1(1):e20220012. doi: 10.1002/SMMD.20220012

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© 2022 The Authors. Smart Medicine published by Wiley‐VCH GmbH on behalf of Wenzhou Institute, University of Chinese Academy of Sciences.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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The antibacterial effect of the AgNPs and AgNPs‐loaded HHPMs against Staphylococcus aureus and Escherichia coli. The results of MIC and MBC analyzes for (A) AgNPs and (B) AgNPs‐loaded HHPMs. The concentration mentioned in panel (B) represents AgNPs relative concentration converted by drug loading efficiency from HHPMs. (C) Antibacterial ratio of 300, 600, and 900 μg/mL AgNPs‐loaded HHPMs in physiological microenvironment (PME) and infection microenvironment (IME). (**p < 0.01). (D) Inhibitory effects of AgNPs‐loaded HHPMs on the growth of S. aureus and E. coli in LB liquid media.