Figure 3 –

(A) CD8⁺ T cell infiltration is significantly increased in carboplatin treated groups compared to anti-VEGFR-2 with (B) elevated levels of CD4⁺ T cells noted across all treatment groups. (C) Representative photomicrographs of IHC-stained tissue sections show co-localization of CD8⁺ and CD4⁺ TIL populations in the carboplatin and anti-PD-1 treated groups and sparse detection in control or anti-VEGFR-2 groups. (n = 3–4 mice per group, in 2 experiments)