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. 2024 Jun 15;16(6):2610–2630. doi: 10.4251/wjgo.v16.i6.2610

Table 3.

Cox regression with stepwise variable reduction

Dependent: Survival (time, status)

HR (univariable)
HR (multivariable)
Age Mean (SD) 1.02 (1.01-1.02, P < 0.001) 1.01 (1.01-1.02, P < 0.001)
Sex Female - -
Male 1.00 (0.93-1.07, P = 0.999) -
Race White - -
Black 0.91 (0.82-1.02, P = 0.109) 0.89 (0.75-1.05, P = 0.165)
Other 0.77 (0.71-0.85, P < 0.001) 0.84 (0.73-0.96, P = 0.009)
Tumor size < 2 - -
2-5 1.27 (1.07-1.52, P = 0.008) 1.08 (0.83-1.40, P = 0.558)
> 5 1.98 (1.66-2.36, P < 0.001) 1.41 (1.09-1.82, P = 0.009)
Unknown 2.24 (1.86-2.70, P < 0.001) 1.69 (1.29-2.22, P < 0.001)
Grade G1/G2 - -
G3/G4 1.11 (0.89-1.37, P = 0.348) -
Unknown 1.16 (0.90-1.51, P = 0.245) -
Primary site Body - -
Cardia 1.16 (1.00-1.35, P = 0.051) 1.23 (0.98-1.53, P = 0.071)
Fundus 1.07 (0.83-1.38, P = 0.608) 1.14 (0.78-1.65, P = 0.503)
Gastric antrum 1.11 (0.97-1.26, P = 0.135) 1.06 (0.87-1.30, P = 0.551)
Greater curvature 1.02 (0.84-1.23, P = 0.878) 1.25 (0.96-1.64, P = 0.103)
Lesser curvature 0.90 (0.78-1.05, P = 0.190) 1.00 (0.79-1.27, P = 0.972)
Pylorus 1.07 (0.88-1.30, P = 0.492) 1.09 (0.82-1.46, P = 0.545)
Overlapping lesion 1.53 (1.32-1.78, P < 0.001) 1.38 (1.10-1.73, P = 0.005)
Unknown 1.45 (1.24-1.69, P < 0.001) 1.34 (1.06-1.69, P = 0.014)
Pathologic stage IB - -
IIA 1.37 (1.01-1.85, P = 0.045) 1.59 (0.98-2.59, P = 0.062)
IIB 1.94 (1.44-2.61, P < 0.001) 2.37 (1.47-3.84, P < 0.001)
IIIA 5.54 (4.14-7.40, P < 0.001) 3.41 (2.13-5.44, P < 0.001)
IIIB 2.73 (2.05-3.65, P < 0.001) 4.86 (3.05-7.76, P < 0.001)
IIIC 3.83 (2.87-5.10, P < 0.001) 7.42 (4.62-11.92, P < 0.001)
Lymph node count Mean (SD) 0.99 (0.99-1.00, P < 0.001) 0.98 (0.98-0.98, P < 0.001)
Chemotherapy status No/unknown -
Yes 0.64 (0.59-0.69, P < 0.001)
Radiation status No/unknown - -
Yes 0.63 (0.59-0.68, P < 0.001) 0.69 (0.62-0.77, P < 0.001)

For race, ‘other’ includes American Indian, AK Native, Asian, and Pacific Islander. HR: Hazard ratio.