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. 2024 Jul 5;15(4):662–674. doi: 10.14740/wjon1869

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Copyright 2024, Ji et al.

This article is distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Survival analysis of hub genes and several immune cells. (a) Downregulation of eight hub genes, including ACADM, ACO2, NDUFS1, PDHB, SDHD, SUCLA2, SUCLG1, and SUCLG2, correlates with shorter overall survival of kidney renal clear cell carcinoma (KIRC) patients. (b) Functional interaction network of the eight hub genes using GeneMANIA algorithm. (c-g) Correlation between infiltration levels of various immune cells and survival of KIRC patients. (c) Activated CD4⁺ T cells. (d) Effector memory CD8⁺ T cells. (e) Regulatory T cells. (f) Macrophage. (g) CD56bright natural killer cells.