Senturk 2013.

Methods	Randomised controlled trial undertaken in Turkey.
Participants	Women undergoing elective or urgent CS. Exclusion criteria ‐ high BMI, venous thromboembolism, uterine myoma, active liver or kidney diseases, polyhydramnios and overweight fetus, allergies to TA or other drugs, especially NSAID, or patients receiving antithrombotic treatment.
Interventions	Intervention group (N = 122) ‐ 1 g TA in 20 mL 5% glucose IV over 5 minutes 10 minutes before anaesthesia. Control group (N = 101) ‐ 20 mL 5 % glucose solution administered in the same manner as in intervention group. All patients received 20 IU oxytocin IV in bolus form after removal of placenta.
Outcomes	Blood loss (from incision until opening of the amniotic sac and then from placental separation until the end of surgery). Other outcomes ‐ haemoglobin difference, haematocrit difference, red blood cell count difference, pre‐ and postoperative haemoglobin.
Notes	All patients were operated under spinal anaesthesia by 2 surgeons.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	High risk	Random number table.
Allocation concealment (selection bias)	High risk	Not described.Discrepancy in numbers (122 vs 101).
Blinding (performance bias and detection bias) All outcomes	Unclear risk	Double‐blind in title, but no description in methods.
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Double‐blind in title, but no description in methods.
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Double‐blind in title, but no description in methods.
Incomplete outcome data (attrition bias) All outcomes	Low risk	Complete data.
Selective reporting (reporting bias)	Unclear risk	No prior registration of protocol.
Other bias	High risk	No description of blinding.