Bhavana 2013.

Methods	Randomised controlled trial.
Participants	200 term pregnant women.
Interventions	Intervention group (N = 100) received IV 1 g TA in 20 mL 5% dextrose and before CS. Control group (N = 100) received 20 mL normal saline. All participants received 10 U oxytocin IM after delivery of neonate.
Outcomes	Blood loss occurred during and 6 hours after surgery; requirement of additional oxytocics; blood transfusion; side effects and adverse effects.
Notes	The blood loss estimated during surgery was less in the TA group (511.3 +/‐164.45 mL) than the control group (637.9+/‐429.77 mL) P < 0.0065. The blood loss in the postoperative period for 6 hours was less in the TA group (P < 0.0015).The need for additional oxytocics and blood transfusion was less in the TA group. Similarly the drop of haemoglobin and haematocrit after surgery was less in the TA group. Side effects observed were mild nausea, vomiting, diarrhoea. No difference in Apgar score and birthweight of neonates was observed in both of the groups. The abstract does not contain sufficient information on study design (randomisation, allocation concealment) for appraisal.

CS: caesarean section
 IM: intramuscularly
 IV: intravenously
 TA: tranexamic acid