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. 2024 Jun 27;14:1389177. doi: 10.3389/fonc.2024.1389177

Table 1.

Baseline patient characteristics in training and validation cohort.

Characteristics Training cohort Validation cohort
BA-active
(n = 41)
BA-inactive
(n = 37)
p-value BA-active
(n = 28)
BA-inactive
(n = 25)
p-value
Age 0.862 0.823
≤50 years 36 32 22 19
>50 years 5 5 6 6
Sex 0.764 0.232
Male 18 15 10 13
Female 23 22 18 12
Smoking 0.274 0.487
No 16 19 13 14
Yes 25 18 15 11
Calcification type <0.001 <0.001
I 2 13 1 12
II 23 20 15 11
III 16 4 12 2
WBC 0.848 0.883
≤9.5×109/L 36 33 25 22
>9.5×109/L 5 4 3 3
NE 0.561 0.122
≤6.3×109/L 39 34 27 21
>6.3×109/L 2 3 1 4
LY 0.368 0.486
≤3.2×109/L 35 34 27 23
>3.2×109/L 6 3 1 2
Fib <0.001 <0.001
≤4 g/L 39 14 23 3
>4 g/L 2 23 5 22
PLT 0.731 0.471
≤350 g/L 38 35 24 23
>350 g/L 3 2 4 2
Crea 0.116 0.340
≤110 µmol/L 36 36 27 25
>110 µmol/L 5 1 1 0
TBIL 0.070 0.205
≤22 µmol/L 27 31 18 20
>22 µmol/L 14 6 10 5
AST 0.220 0.275
≤59 U/L 27 29 20 21
>59 U/L 14 8 8 4
ALT 0.092 0.552
≤72 U/L 29 32 23 22
>72 U/L 12 5 5 3
PT 0.560 0.805
≤38 s 27 22 17 16
>38 s 14 15 11 9

BA, bioactivity; WBC, white blood cells; NE, neutrophils count; LY, lymphocyte count; Fib, fibrinogen; PLT, platelet count; Crea, creatinine; TBIL, total bilirubin; ASL, aspartate aminotransferase; ALT, alanine aminotransferase; PT, prothrombin time.