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. 2024 Jun 27;14:1389177. doi: 10.3389/fonc.2024.1389177

Table 4.

Prediction performance of different machine learning models in training and validation cohort.

Classifiers Training cohort Validation cohort
AUC (95% CI) Accuracy Sensitivity Specificity AUC (95% CI) Accuracy Sensitivity Specificity
SVM 0.791 (0.781–0.802) 82.60% 75.30% 90.30% 0.776 (0.766–0.786) 73.80% 71.30% 76.60%
KNN 0.765 (0.754–0.775) 77.20% 70.50% 84.20% 0.716 (0.706–0.726) 67.70% 65.10% 70.50%
RF 0.711 (0.699–0.723) 77.60% 69.00% 86.90% 0.685 (0.673–0.697) 68.20% 67.40% 69.20%
DT 0.729 (0.718–0.740) 75.10% 67.70% 83.20% 0.647 (0.634–0.661) 64.70% 61.60% 68.10%
LR 0.783 (0.773–0.794) 81.50% 74.70% 88.70% 0.761 (0.752–0.771) 72.60% 69.60% 72.50%

SVM, support vector machine; KNM, k-nearest neighbor); RF, random forest; DT, decision tree; LR, logistic regression; AUC, the area under the curve.