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. 2024 Jul 3;631(8020):386–392. doi: 10.1038/s41586-024-07626-3

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 10 — (a) NVT-penicillin resistant (red), (b) NVT-penicillin susceptible (green), (c) VT-penicillin resistant (yellow) and (d) VT-penicillin susceptible (blue). The dashed lines indicate the year of PCV7 implementation and fitness switch model implemented. (e) Fitness estimates pre-PCV and post-PCV for each group and colored accordingly. e is on a log scale. This model uses a shift in fitness in 2009. Error bars represent 2.5 to 97.5 percentiles.