| • Depressed mood† | • Decreased interest or pleasure† |
| • Substantial weight loss or weight gain | • Psychomotor retardation or agitation |
| • Insomnia or hypersomnia | • Fatigue or loss of energy |
| • Feelings of worthlessness or inappropriate guilt | • Diminished ability to think or concentrate |
| • Recurrent thoughts of death or suicide or suicide attempt | |
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