Table 2.
Weighted multivariate linear analysis SII and senescence for phenotypic age acceleration.
| Characteristics | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|
| β (95% CI) | p value | β (95% CI) | p value | β (95% CI) | p value | |
| Log (SII) | 3.89 (3.49, 4.28) | <0.0001 | 4.34 (3.94, 4.75) | <0.0001 | 3.7 (3.32, 4.09) | <0.0001 |
| Stratified by SII quartiles | ||||||
| Q1 | 1.00 (1.00, 1.00) | 1.00 (1.00, 1.00) | 1.00 (1.00, 1.00) | |||
| Q2 | 1.46 (1.02, 1.90) | <0.0001 | 1.87 (1.44, 2.30) | <0.0001 | 1.55 (1.15, 1.94) | <0.0001 |
| Q3 | 2.59 (2.14, 3.05) | <0.0001 | 3.07 (2.61, 3.53) | <0.0001 | 2.61 (2.20, 3.01) | <0.0001 |
| Q4 | 5.58 (5.10, 6.06) | <0.0001 | 6.22 (5.75, 6.69) | <0.0001 | 5.28 (4.85, 5.71) | <0.0001 |
Model 1: unadjusted mode; Model 2: adjusted for age, sex, race; Model 3: additionally adjusted for age, sex, BMI, race/ethnicity, marital status, education, smoking, alcohol intake, poverty, diabetes, hypertension, CVD, cancer, and physical activity. Q1 represents the range of SII within [7.1505, 347.885]. Q2 represents the range of SII within [347.885, 482]. Q3 represents the range of SII within [482, 676]. Q4 represents the range of SII within [676, 7290.9375].