Table 7.

AUC parameters of CXCL8, tumor markers and inflammatory factors in clinical staging

Marker	AUC	95% CI	Specificity	Sensitivity	Youden index	Cut off
CEA	0.595	0.501-0.595	64.52%	56.32%	20.84%	3.895
CXCL8	0.708	0.625-0.708	80.65%	54.02%	34.67%	343.085
CYFRA21-1	0.672	0.585-0.672	91.94%	37.93%	29.87%	6.935
hs-CRP	0.604	0.513-0.604	56.45%	64.37%	20.82%	13.705

Notes: CXCL8: chemokine-8; hs-CRP: high sensitivity C-reactive protein; CEA: carcinoembryonic antigen; CYFRA21-1: cytokeratin 19 fragment; ROC: receiver operating characteristic curve.