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. 2024 Jun 25;14(6):3171–3185. doi: 10.62347/MUKD2745

Figure 6.

Figure 6

Validation of MDSC abundance and Csf3r mRNA expression in clinical PBMC datasets. Boxplots of MDSC signature in (A) monocytes from patients with metastatic breast cancer compared with healthy donors and (B) whole blood from patients with TNBC with recurrence compared with those without recurrence. Boxplot of Csf3r mRNA expression in (C) monocytes and (D) whole blood from patients with metastatic breast cancer and patients with TNBC with recurrence, respectively. (E) CD14+/CD15-/CSF3R+ cell population of 35 patients with breast cancer, 29 with no recurrence (median = 544, 544/10000 cells) and 6 with recurrence (median = 650, 650/10000 cells). (F) Kaplan-Meier survival curve of 35 patients.