Fig. 3. Mitotic and apoptotic activities are well-approximate by the logistic equation.
a Relative CDK1 activity as a function of time at mitotic onset, normalized to a maximal activity of 1, as measured by H1 kinase activity assay, can be well-fitted by a logistic model. Data are taken from Pomerening et al.41. b Apoptosis as a function of time, measured at one point in a Teflon tube of extract. Fluorescence was followed as a function of time by microscopy. c Kinetics of (Z-DEVD)2-R110 cleavage. Open circles are data at each time point. The red curve is based on the ODE model for caspase 3/7 activation and (Z-DEVD)2-R110 cleavage (Eq. 16) fitted to the data. d Kinetics of caspase 3/7 activation. Open circles are concentrations of active caspase 3/7 calculated based on the ODE model (Eq. 15). The red curve is the logistic equation fitted to the data. Source data are provided as a Source Data file.