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. 2024 Jul 10;14:15893. doi: 10.1038/s41598-024-66905-1

Table 2.

Distribution of transmitted drug resistance according to ARV classes and demographic characteristics of the Angolan naïve patients.

Independent variable N (%) NRTI mutation NNRTI mutation PI mutation
No (%) Yes (%) p-value No (%) Yes (%) p-value No (%) Yes (%) p-value
Overall 45 (100) 44 (97.8) 1 (2.2) 36 (80.0) 9 (20.0) 44 (97.8) 1 (2.2)
Age distribution
 ≤ 30 years 19 (42.2) 19 (100) 0 (0.0) 1.000 13 (68.4) 6 (31.6) 0.137 18 (94.7) 1 (5.3) 0.422
 > 30 years 26 (57.8) 25 (96.2) 1 (3.8) 23 (88.5) 3 (11.5) 26 (100) 0 (0.0)
Sex
 Female 5 (11.1) 5 (100) 0 (0.0) 1.000 4 (80.0) 1 (20.0) 1.000 5 (100) 0 (0.0) 1.000
 Male 40 (88.9) 39 (97.5) 1 (2.5) 32 (80.0) 8 (20.0) 39 (97.5) 1 (2.5)
Residence área
 Non-urbanized 23 (51.1) 23 (100) 0 (0.0) 0.489 18 (78.3) 5 (21.7) 0.766 23 (100) 0 (0.0) 0.489
 Urbanized 22 (48.9) 21 (95.5) 1 (4.5) 18 (81.8) 4 (18.2) 21 (95.5) 1 (4.5)
Occupation
 Unemployed 8 (17.8) 7 (87.5) 1 (12.5) 0.030 6 (75.0) 2 (25.0) 0.651 8 (100) 0 (0.0) 0.638
 Employed 37 (82.2) 37 (100) 0 (0.0) 30 (81.1) 7 (18.9) 36 (97.3) 1 (2.7)
HIV-1 subtypes
 C 16 (35.6) 16 (100) 0 (0.0) 0.593 11 (68.8) 5 (31.3) 0.609 15 (93.8) 1 (6.3) 0.967
 F1 7 (15.6) 6 (85.7) 1 (14.3) 5 (71.4) 2 (28.6) 7 (100) 0 (0.0)
 G 5 (11.1) 5 (100) 0 (0.0) 5 (100) 0 (0.0) 5 (100) 0 (0.0)
 A1 5 (11.1) 5 (100) 0 (0.0) 4 (80.0) 1 (20.0) 5 (100) 0 (0.0)
 H 3 (6.7) 3 (100) 0 (0.0) 2 (66.7) 1 (33.3) 3 (100) 0 (0.0)
 D 2 (4.4) 2 (100) 0 (0.0) 2 (100) 0 (0.0) 2 (100) 0 (0.0)
 CRF02_AG 2 (4.4) 1 (100) 0 (0.0) 2 (100) 0 (0.0) 2 (100) 0 (0.0)
 Other HIV-1 strains 5 (11.1) 5 (100) 0 (0.0) 5 (100) 0 (0.0) 5 (100) 0 (0.0)

Bold number indicate statistical significance for the Chi-square test or Fisher's exact test (p < 0.05).