Fig. 5. Scope for the ¹⁸F-2,2,2-trifluoroethoxylation of aromatic and aliphatic substrates.

LG = leaving group. Yields are calculated from HPLC analyses of crude reaction mixtures and based are [¹⁸F]fluoroform conversion into the products. Radioactive products were collected at least once for each substrate to confirm that HPLC yields match isolated yields. All yields are decay-corrected and reported as mean ± SD for n = 3. A Substrate scope for homoarenes using reaction condition (B). B Substrate scope for heteroarenes using reaction condition (B). C Substrate scope for aliphatic compounds using reaction condition (B).