TABLE 1.
Baseline clinical characteristics of the patients in intravenous thrombolysis (IVT) group.
| Total (n = 90) | Good outcome mRS (n = 46) | Poor outcome mRS (2–6) (n = 44) | p‐Value | |
|---|---|---|---|---|
| Characteristics mean ± SD/N (%) | ||||
| Age, years | 70.99 ± 9.68 | 71.43 ± 9.29 | 70.52 ± 10.17 | .66 |
| Sex | 56 (62.22%) | 31 (67.39%) | 25 (56.82%) | .41 |
| Vascular risk factors, N (%) | ||||
| Hypertension | 68 (75.56%) | 33 (71.74%) | 35 (79.55%) | .54 |
| Diabetes mellitus | 26 (28.89%) | 18 (39.13%) | 8 (18.18%) | .05 |
| Active smokers | 39 (43.33%) | 21 (45.65%) | 18 (40.91%) | .81 |
| Drink | 31 (34.44%) | 18 (39.13%) | 13 (29.55%) | .46 |
| History of CI | 8 (8.89%) | 2 (4.35%) | 6 (13.64%) | .15 |
| History of CH | 1 (1.11%) | 0 (0.00%) | 1 (2.27%) | .49 |
| Atrial fibrillation | 39 (43.33%) | 20 (43.48%) | 19 (43.18%) | 1.00 |
| Myocardial infarct | 4 (4.44%) | 2 (4.35%) | 2 (4.55%) | 1.00 |
| HCY | 11.63 (10.02, 13.66) | 11.63 (9.84, 13.28) | 11.63 (10.09, 13.85) | .45 |
| Systolic pressure | 168 (155, 184.5) | 168 (157.25, 181.75) | 171 (151.75, 191) | .57 |
| Diastolic pressure | 92 (83, 102.75) | 91.5 (86, 100.75) | 93 (76.75, 106.25) | .92 |
| NIHSS | 7.5 (5, 12.75) | 5.5 (4, 7) | 11 (8, 14.25) | .00 |
| DNT | 30 (25.25, 49.75) | 29 (25.25, 47.75) | 38 (25.75, 54.25) | .27 |
| WBC d0 | 7.53 (5.96, 9.48) | 6.83 (5.51, 9.27) | 7.86 (6.62, 9.63) | .10 |
| WBC d1 | 7.47 (6.14, 9.07) | 6.67 (5.31, 8.35) | 8.29 (7.29, 9.7) | .00 |
| WBC d3 | 7.22 (5.72, 8.31) | 6.38 (5.39, 7.83) | 7.76 (6.94, 8.95) | .00 |
| WBC d7 | 6.63 ± 1.97 | 6.01 ± 2.06 | 7.28 ± 1.67 | .00 |
| Neutrophil counts (109/L) d0 | 4.73 (3.75, 6.53) | 4.38 (3.62, 6.13) | 4.95 (3.96, 6.94) | .08 |
| Neutrophil counts (109/L) d1 | 5.59 (4.11, 7.02) | 4.42 (3.54, 5.88) | 6.32 (5.48, 7.98) | .00 |
| Neutrophil counts (109/L) d3 | 5.08 (3.82, 6.22) | 4.3 (3.25, 5.53) | 5.65 (4.94, 6.84) | .00 |
| Neutrophil counts (109/L) d7 | 4.4 (3.13, 5.26) | 3.47 (2.72, 4.8) | 4.96 (4.21, 5.82) | .00 |
| Lymphocyte counts (109/L) d0 | 1.61 (1.21, 2.45) | 1.68 (1.24, 2.68) | 1.41 (1.2, 2.26) | .63 |
| Lymphocyte counts (109/L) d1 | 1.3 (1.02, 1.68) | 1.48 (1.11, 1.83) | 1.26 (0.99, 1.52) | .11 |
| Lymphocyte counts (109/L) d3 | 1.44 (1.1, 1.8) | 1.58 (1.24, 1.94) | 1.32 (1.05, 1.71) | .03 |
| Lymphocyte counts (109/L) d7 | 1.44 (1.15, 1.83) | 1.49 (1.19, 1.84) | 1.39 (1.14, 1.8) | .50 |
| NLR d0 | 2.93 (1.66, 4.47) | 2.5 (1.61, 3.48) | 3.58 (1.79, 5.06) | .08 |
| NLR d1 | 4.25 (2.87, 6.14) | 3.39 (2.35, 4.33) | 5.66 (4.12, 6.97) | .00 |
| NLR d3 | 3.37 (2.52, 4.5) | 2.64 (2.04, 3.52) | 4.22 (3.14, 5.55) | .00 |
| NLR d7 | 2.82 (2.1, 3.85) | 2.34 (1.92, 3.09) | 3.8 (2.7, 4.34) | .00 |
| Monocyte counts (109/L) d0 | 0.42 (0.34, 0.55) | 0.42 (0.34, 0.57) | 0.42 (0.34, 0.54) | .92 |
| Monocyte counts (109/L) d1 | 0.46 (0.37, 0.56) | 0.42 (0.31, 0.55) | 0.47 (0.38, 0.55) | .18 |
| Monocyte counts (109/L) d3 | 0.5 (0.38, 0.6) | 0.44 (0.33, 0.59) | 0.54 (0.44, 0.63) | .01 |
| Monocyte counts (109/L) d7 | 0.43 (0.35, 0.54) | 0.4 (0.3, 0.5) | 0.46 (0.41, 0.56) | .02 |
| PLT d0 | 178 (142.25, 208) | 185 (137.5, 209.5) | 178 (143.75, 205.25) | .73 |
| PLT d1 | 169 (133.5, 204.5) | 171 (132.25, 204) | 168.5 (136.5, 205.75) | .68 |
| PLT d3 | 165 (136.75, 204.25) | 162 (132.5, 205.75) | 166.5 (139, 191.25) | .90 |
| PTL d7 | 182.5 (155.25, 208.25) | 175.5 (140, 201.5) | 190 (165, 211.5) | .22 |
Abbreviations: CH, cerebral hemorrhage; CI, cerebral infarction; DNT, door‐to‐needle time; HCY, homocysteine; mRS, modified Rankin scale; NIHSS, National Institutes of Health Stroke Scale; NLR, neutrophil‐to‐lymphocyte ratio; PLT, platelet; SD, standard deviation; WBC, white blood cell.