Table 2.

Changes in irisin and FGF-21 levels throughout 16 weeks of aquatic and land exercise

Variable	Group (n=10)	First	Second	Third	Change	Paired t-test	F
Irisin (ng/mL)	CG	166.67±15.44		164.37±14.85	−2.30±13.27	−0.548	Group (G)	4.480*
	AEG	169.64±12.93	185.67±17.19	198.43±21.31	28.80±29.29	3.108*	Time (T)	5.909**
	LEG	172.70±12.63	176.86±12.32	175.87±15.89	3.17±19.44	0.516	G×T	3.717*
	F	0.483		9.715**	5.846**
	Post-hoc	NS		CG, LEG<AEG	CG, LEG<AEG
FGF-21 (pg/mL)	CG	95.29±18.19		93.93±21.62	−1.36±22.54	−0.191	Group (G)	4.651*
	AEG	91.14±9.57	100.35±9.57	111.83±12.56	20.69±14.83	4.413*	Time (T)	14.885***
	LEG	92.46±9.15	94.07±7.53	94.06±7.34	1.60±5.25	0.964	G×T	11.066***
	F	0.267		4.686*	5.690**
	Post-hoc	NS		CG, LEG<AEG	CG, LEG<AEG

Values are presented as mean±standard deviation.

FGF-21, fibroblast growth factor 21; first, before the 16-week exercise program; second, 30 minutes after the first exercise session; third, 30 minutes after the last exercise session; CG, control group; AEG, aquatic exercise group; LEG, land exercise group; NS, non-significant.

^*p<0.05,

^**p<0.01,

^***p<0.001.