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. 2024 Apr 29;15(6):e00581-24. doi: 10.1128/mbio.00581-24

Fig 4.

Mapping of covarying SNPS; schematic of gene organization; and functional impact of the introgressed genes on FDH activity are in respective illustrations.

Genomic context and physiological roles of introgressed epistatically linked genes involved in FDH biogenesis and activity. (A) The position of putative epistatic sites mapped on the C. coli CVM29710 reference for co-varying C. jejuni-C. jejuni SNPs (blue) in 16 gene pairs (a to l) and other haplotype combinations (gray). (B) Genome organization of the most common co-varying introgressed C. jejuni-C. jejuni gene pairs linked to FDH. (C and D) FDH activity of whole cells determined by oxygen consumption rates in a Clark-type electrode (nanomoles of oxygen consumed per minute per milligram of total protein) for (C) cells grown in rich media (excess selenium) and (D) cells grown in minimal media with 0.5 nM sodium selenite. *** denotes P value of <0.001 by Student’s t-test.