Fig 4.

Differential enrichment of colonic microbiota. Analysis of taxonomic abundance using linear discriminant analysis effect size (LEfSe) (LDA score ≥ 2, P < 0.05) in the colonic contents of offspring piglets at 65 (a), 95 (b), and 125 (c) days old. The cladogram shows the microbial species with a significant difference between the experiment group and the control group in LEfSe analysis. C, control group; SOA, antibiotic supplementation in sow-offspring diets; SOP, probiotic supplementation in sow-offspring diets; SOS, synbiotic supplementation in sow-offspring diets. The replicates per group at 65 days old were 8. The replicates of the C, SOA, SOP, and SOS groups at 95 days old were 8, 8, 8, and 7, respectively. The replicates of the C, SOA, SOP, and SOS groups at 125 days old were 8, 5, 6, and 6, respectively.