Fig 2.

Effects of CLR signaling on T cell accumulation in the lungs after C. deneoformans infection WT (n = 3), CARD9KO (A, n = 3), Dectin-2KO (B, n = 5), and MincleKO (C, n = 4) mice were infected intratracheally with C. deneoformans. The number of each T cell subset was analyzed using flow cytometry on day 3 post-infection. Each column represents the mean ± SD. *, P < 0.05. ***, P < 0.005. Representative data demonstrating similar results from independent experiments are shown. Experiments were conducted three times for A and B and twice for C. The results for A and C represent experiments conducted simultaneously, and the outcomes for WT mice utilize the same materials.