TABLE 1.
Demographic characteristics of sputum-producing participants
| Parameter | All n = 23 | CF n = 17 (73.9%) | NCFB n = 4 (17.4%) | PCD n = 2 (8.7%) | P-valuea |
|---|---|---|---|---|---|
| Age in years, med (IQR) | 37 (23.5–46) | 25 (22–37) | 70 (66.8–72) | 50 (49.5–50.5) | 0.5585 |
| Female, n (%) | 13 (56.5%) | 9 (52.9%) | 2 (50%) | 2 (100%) | 0.2090 |
| Race, n (%) | 0.2432 | ||||
| Caucasian/White | 16 (69.6%) | 12 (70.6%) | 3 (75%) | 1 (50%) | |
| African American/Black | 7 (30.4%) | 5 (29.4%) | 1 (25%) | 1 (50%) | |
| CFTRb genotype, n (%) | – | ||||
| F508del homozygous | – | 7 (41.2%) | – | – | |
| F508del heterozygous | – | 6 (35.3%) | – | – | |
| No F508del mutation | – | 4 (23.5%) | – | – | |
| ppFEV1c, mean ± SD | 51.9 ± 15.7 | 53.6 ± 14.3 | 54.3 ± 19.3 | 34.3 ± 4.5 | 0.6053 |
a
Correlation P-value between demographic parameter and ex vivo antibiotic tolerance in Fig. 1.
b
CFTR, cystic fibrosis transmembrane conductance regulator.
c
ppFEV1, percent predicted forced expiratory volume in 1 s.