Table 3.

Results of separate linear mixed effects regression models showing significant relationships between battery percentage trajectories throughout the day and executive functioning, memory, language, visuospatial skills, neuropsychiatric symptoms, and whole brain gray matter volume (lower order terms and covariates are not displayed).

			β (95% CI)		P value
Executive functioning
	Time of day (linear)×UDS3-EFa composite score	.24 (.17 to .31)		<.001
	Time of day (quadratic)×UDS3-EF composite score	−.65 (−.80 to −.50)		<.001
	Time of day (cubic)×UDS3-EF composite score	.38 (.28 to .47)		<.001
Memory
	Time of day (linear)×memory z score	.21 (.13 to .28)		<.001
	Time of day (quadratic)×memory z score	−.58 (−.74 to −.42)		<.001
	Time of day (cubic)×memory z score	.34 (.24 to .44)		<.001
Language
	Time of day (linear)×MINTb z score	.07 (.00 to .15)		.05
	Time of day (quadratic)×MINT z score	−.24 (−.40 to −.08)		.002
	Time of day (cubic)×MINT z score	.15 (.05 to .25)		.004
Visuospatial skills
	Time of day (linear)×Benson Complex Figure Copy z score	.10 (.04 to .16)		.001
	Time of day (quadratic)×Benson Complex Figure Copy z score	−.28 (−.38 to −.19)		<.001
	Time of day (cubic)×Benson Complex Figure Copy z score	.19 (.13 to .25)		<.001
Neuropsychiatric symptoms
	Time of day (linear)×NPIc total score	−.06 (−.13 to .01)		.08
	Time of day (quadratic)×NPI total score	.25 (.10 to .39)		.001
	Time of day (cubic)×NPI total score	−.15 (−.25 to −.05)		.002
Gray matter volume (n=189)
	Time of day (linear)×gray matter volume	.22 (.14 to .29)		<.001
	Time of day (quadratic)×gray matter volume	−.73 (−.88 to −.57)		<.001
	Time of day (cubic)×gray matter volume	.45 (.35 to .55)		<.001

^aUDS3-EF: Uniform Data Set (Version 3) Executive Function.

^bMINT: Multilingual Naming Test.

^cNPI: Neuropsychiatric Inventory.