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. 2024 Jun 27;9(27):29870–29883. doi: 10.1021/acsomega.4c03796

Table 2. IPF Associated Target Gene Information.

  Uniprot ID name ensemble ID genes DSI DPI
1 P01137 transforming growth factor beta-1 proprotein ENSG00000105329 TGFB1 0.287 0.962
2 P61812 transforming growth factor beta-2 proprotein ENSG00000092969 TGFB2 0.433 0.885
3 P16234 platelet-derived growth factor receptor alpha″ PDGFR-a 0.415 0.808
4 P09038 fibroblast growth factor 2 ENSG00000138685 FGF-2 0.383 0.923
5 P84022 mothers against decapentaplegic homologue 3 ENSG00000166949 Smad3 0.415 0.923
6 P31751 RAC-beta serine/threonine-protein kinase ENSG00000105221 Akt-2 0.474 0.769
7 P62736 smooth muscle actinn-alpha ENSG00000107796 a-SMA 0.54 0.769
8 P02452 collagen alpha-1(I) chain″ ENSG00000108821 0.43 0.846
9 Q8QHL3 vascular endothelial growth factor receptor 1   VEGFR 0.419 0.846
10 P08253 72 kDa type IV collagenase ENSG00000087245 MMP-2 0.333 0.923
11 P29279 connective tissue growth factor ENSG00000118523 CTGF 0.399 0.846
12 Q5VWK5 interleukin-23 receptor ENSG00000162594 IL-23 0.415 0.846
13 P05231 interleukin-6 ENSG00000136244 IL-6 0.248 0.962
14 P05121 plasminogen activator inhibitor 1 ENSG00000106366 PAI-1 0.359 0.885
15 P35225 interleukin-13 ENSG00000169194 IL-13 0.846 0.846
16 P24394 interleukin-4 receptor subunit alpha ENSG00000077238 IL-4Ra 0.474 0.846