Table 3. Drugs Already Used under IPF and Other Related Conditions.

	DrugBank ID	name	ensemble gene ID (ensemble)	disease genes
idiopathic pulmonary fibrosis (IPF)
1	DB00175	pravastatin	ENSG00000105221	Akt-2
2	DB00184	nicotine	ENSG00000105221	Akt-2
3	DB00201	caffeine	ENSG00000105221	Akt-2
4	DB00248	cabergoline	ENSG00000105221	Akt-2
5	DB00321	amitriptyline	ENSG00000105221	Akt-2
6	DB00333	methadone	ENSG00000105221	Akt-2
7	DB00341	cetirizine	ENSG00000105221	Akt-2
8	DB00370	mirtazapine	ENSG00000105221	Akt-2
9	DB00437	allopurinol	ENSG00000106366	PAI-1
10	DB00458	imipramine	ENSG00000105221	Akt-2
11	DB00468	quinine	ENSG00000105221	Akt-2
12	DB00471	montelukast	ENSG00000087245	MMP-2
13	DB00480	lenalidomide	ENSG00000106366	PAI-1
14	DB00493	cefotaxime	ENSG00000105221	Akt-2
15	DB00502	haloperidol	ENSG00000105221	Akt-2
16	DB00514	dextromethorphan	ENSG00000105221	Akt-2
17	DB00517	anisotropine methyl bromide	ENSG00000105221	Akt-2
18	DB00548	azelaic acid	ENSG00000105221	Akt-2
19	DB00557	hydroxyzine	ENSG00000105221	Akt-2
20	DB00562	benzthiazide	ENSG00000105221	Akt-2
21	DB00565	cisatracurium	ENSG00000105221	Akt-2
22	DB00570	vinblastine	ENSG00000106366	PAI-1
23	DB00590	doxazosin	ENSG00000105221	Akt-2
24	DB00598	labetalol	ENSG00000105221	Akt-2
25	DB00641	simvastatin	ENSG00000105221	Akt-2
26	DB00661	verapamil	ENSG00000105221	Akt-2
27	DB00678	losartan	ENSG00000106366	PAI-1
28	DB00808	indapamide	ENSG00000105221	Akt-2
29	DB00843	donepezil	ENSG00000105221	Akt-2
30	DB00844	nalbuphine	ENSG00000105221	Akt-2
31	DB00850	perphenazine	ENSG00000105221	Akt-2
32	DB00852	pseudoephedrine	ENSG00000105221	Akt-2
33	DB00920	ketotifen	ENSG00000105221	Akt-2
34	DB00924	cyclobenzaprine	ENSG00000105221	Akt-2
35	DB00972	azelastine	ENSG00000105221	Akt-2
36	DB00975	dipyridamole	ENSG00000105221	Akt-2
37	DB00988	dopamine	ENSG00000105221	Akt-2
38	DB01012	cinacalcet	ENSG00000105221	Akt-2
39	DB01039	fenofibrate	ENSG00000105221	Akt-2
40	DB01056	tocainide	ENSG00000105221	Akt-2
41	DB01095	fluvastatin	ENSG00000105221	Akt-2
42	DB01098	rosuvastatin	ENSG00000105221	Akt-2
43	DB01115	nifedipine		VEGFR
44	DB01148	flavoxate	ENSG00000105221	Akt-2
45	DB01198	zopiclone	ENSG00000105221	Akt-2
46	DB01216	finasteride	ENSG00000105221	Akt-2
47	DB01222	budesonide	ENSG00000105221	Akt-2
48	DB01223	aminophylline	ENSG00000106366	PAI-1
49	DB01303	oxtriphylline	ENSG00000106366	PAI-1
50	DB01406	danazol	ENSG00000105221	Akt-2
51	DB01409	tiotropium	ENSG00000105221	Akt-2
52	DB01656	roflumilast	ENSG00000105221	Akt-2
53	DB04843	mepenzolate	ENSG00000105221	Akt-2
54	DB05039	indacaterol	ENSG00000105221	Akt-2
55	DB05154	pretomanid	ENSG00000106366	PAI-1
56	DB05294	vandetanib	ENSG00000106366	PAI-1
57	DB05812	abiraterone	ENSG00000105221	Akt-2
58	DB05990	obeticholic acid	ENSG00000106366	PAI-1
59	DB06410	doxercalciferol	ENSG00000105221	Akt-2
60	DB06616	bosutinib	ENSG00000087245	MMP-2
61	DB06663	pasireotide	ENSG00000105221	Akt-2
62	DB06772	cabazitaxel	ENSG00000106366	PAI-1
63	DB06800	methylnaltrexone	ENSG00000105221	Akt-2
64	DB08860	pitavastatin	ENSG00000105221	Akt-2
65	DB08896	regorafenib	ENSG00000087245	MMP-2
66	DB08910	pomalidomide	ENSG00000106366	PAI-1
67	DB08916	afatinib	ENSG00000105221	Akt-2
68	DB09053	ibrutinib	ENSG00000105221	Akt-2
69	DB09079	nintedanib	ENSG00000105221	Akt-2
70	DB11217	arbutin	ENSG00000106366	PAI-1
71	DB11619	gestrinone	ENSG00000105221	Akt-2
cystic fibrosis
72	DB00198	oseltamivir	ENSG00000105221	Akt-2
73	DB00462	methscopolamine bromide	ENSG00000105221	Akt-2
74	DB00487	pefloxacin	ENSG00000105221	Akt-2
75	DB01061	azlocillin	ENSG00000106366	PAI-1
76	DB01165	ofloxacin	ENSG00000105221	Akt-2
77	DB01409	tiotropium	ENSG00000105221	Akt-2
78	DB08897	aclidinium	ENSG00000105221	Akt-2
79	DB09076	umeclidinium	ENSG00000105221	Akt-2
lung fibrosis
80	DB00474	methohexital	ENSG00000106366	PAI-1
81	DB00700	eplerenone	ENSG00000105221	Akt-2
82	DB00758	clopidogrel	ENSG00000105221	Akt-2
83	DB00843	donepezil	ENSG00000105221	Akt-2
84	DB01240	epoprostenol	ENSG00000105221	Akt-2
85	DB01587	ketazolam	ENSG00000105221	MMP-2
86	DB01591	solifenacin	ENSG00000105221	MMP-2
87	DB02659	cholic acid	ENSG00000105221	TGFB-1/2
88	DB04854	febuxostat	ENSG00000105221	Akt-2
89	DB08881	vemurafenib	ENSG00000106366	PAI-1
90	DB09477	enalaprilat	ENSG00000105221	Akt-2
91	DB14490	ferrous ascorbate	ENSG00000106366	PAI-1
renal fibrosis
92	DB06212	tolvaptan	ENSG00000105221	Akt-2
93	DB01267	paliperidone	ENSG00000105221	Akt-2
other fibrotic conditions
92	DB00247	methysergide	ENSG00000105221	Akt-2
93	DB00381	amlodipine	ENSG00000105221	Akt-2
94	DB00421	spironolactone	ENSG00000087245	MMP-2
95	DB00425	zolpidem	ENSG00000105221	Akt-2
96	DB00795	sulfasalazine	ENSG00000105221	Akt-2
97	DB00915	amantadine	ENSG00000105221	Akt-2
98	DB00973	ezetimibe	ENSG00000105221	Akt-2
99	DB02300	calcipotriol	ENSG00000105221	Akt-2
100	DB05271	rotigotine	ENSG00000105221	Akt-2
101	DB06209	prasugrel	ENSG00000105221	Akt-2
102	DB06210	eltrombopag	ENSG00000105221	Akt-2
103	DB08867	ulipristal	ENSG00000105221	Akt-2