Fig. 3.

eQTL map across the four tissues. The genomic position of associated genes (y-axis) versus genomic position of the top polymorphism from the eQTL (x-axis). Each black dot represents a significant association between an associated gene and the most significant SNP of the eQTL region. Diagonal dots represent cis-eQTLs and off-diagonal dots represent trans-eQTLs. The presence of a vertical band suggests that numerous expressed associated genes are linked to a single genomic locus, indicating trans-eQTL hotspots. Conversely, a horizontal band indicate the association between many top polymorphisms from eQTLs and a single gene