Extended Data Table 6.
Comparison of the immune gene repertoire of the Ninu with two marsupial species with partially invasive placentae (Tasmanian devil and opossum) and non-invasive placentae (koala and woylie)
| Immune Gene Family | Ninu (Greater bilby) | Tasmanian devil (Purinina)127 | Short-tailed opossum129 | Koala (Guba)17 | Woylie128 |
|---|---|---|---|---|---|
| Cytokines | 84 | 72 | 76 | 82 | 77 |
| TLR | 10 | 10 | 10 | 10 | 10 |
| MHC-I | 6 | 6 | 6 | 19 | 17 |
| MHC-II | 12 | 8 | 12 | 16 | 23 |
| MHC-III | 38 | 36 | 33 | 39 | 37 |
| Ext. MHC & framework genes | 29 | 32 | 28 | 27 | 31 |
| NKC | 12 | 16 | 15 | 17 | 17 |
| LRC (IG domains) | 92 | 92 | 123 | 51 | 60 |
| Extended LRC | 22 | 16 | 9 | 6 | 22 |
| IG constant | 14 | 11 | 13 | 15 | 20 |
| IG variable | 116 | 61 | 89 | 289 | 226 |
| TCR constant | 9 | 13 | 14 | 10 | 12 |
| TCR variable | 118 | 82 | 67 | 103 | 122 |
| Total | 562 | 385 | 495 | 658 | 674 |
Only species with chromosome length genome assemblies were selected because genome quality influences the ability to characterise immune genes130.