This work presents an expert-informed review on the role of isometric exercise training in the prevention and treatment of arterial hypertension, covering the efficacy, prescription protocols, evidence quality and certainty, acute cardiovascular stimulus, and physiological mechanisms underpinning its anti-hypertensive effect.

Data from prospective randomised controlled trials and meta-analyses indicate that isometric exercise training is capable of producing blood pressure reductions greater than that observed following the currently recommended exercise guidelines and possibly even greater, or at least similar to that of standard anti-hypertensive monotherapy.

Several domains within the literature require further empirical attention; however, current evidence supports the clinical implementation of IET for the management of blood pressure.