Table 1.
Clinical Characteristics of the Study Subjects
| Characteristic | ADEH+ n = 15 | ADEH− n = 13 | HC n = 13 | P-Value, Overall |
|---|---|---|---|---|
| Age, y | ||||
| Mean (SD) | 33.1 (10.5) | 37.7 (11.4) | 41.0 (8.4) | .134 |
| Gender, n (%) | ||||
| Female | 9 (60.0) | 9 (69.2) | 10 (76.9) | .929 |
| Male | 6 (40.0) | 4 (30.8) | 3 (23.1) | |
| Ethnicity, n (%) | ||||
| Hispanic or Latino | 1 (6.7) | 1 (7.7) | 1 (7.7) | .993 |
| Non-Hispanic or Latino | 14 (93.3) | 12 (92.3) | 12 (92.3) | |
| Race, n (%) | ||||
| White | 13 (86.7) | 11 (84.6) | 10 (76.9) | .777 |
| Black or African American | 2 (13.3) | 2 (15.4) | 3 (23.1) | |
| EASI score | ||||
| Mean (SD) | 17.5 (11.0) | 15.9 (14.3) | NA | .749 |
| SCORAD | ||||
| Mean (SD) | 50.8 (13.8) | 43.1 (18.7) | NA | .224 |
| Rajka–Langeland total score | ||||
| Mean (SD) | 7.3 (1.2) | 6.8 (1.8) | NA | .459 |
| Serum IgE | ||||
| Median (1st, 3rd quartile] | 1100 (118, 2400)1,2 | 300 (91.7, 841)3 | 29 (7.5, 44.5) | .0002 |
| Skin Staphylococcus aureus culture positive, n (%) | 11 (73.3) | 8 (61.5) | 0 (0) | .0002 |
Abbreviations: ADEH, atopic dermatitis with eczema herpeticum; EASI, Eczema Area and Severity Index; NA, not applicable; SCORAD, SCORing Atopic Dermatitis.
1
P = .0003 compared with HC.
2
P = .08 compared with ADEH− participants.
3
P = .003 compared with HC.