FIG. 2.

Stimulation of proinflammatory cytokine and chemotactic chemokine levels in lung during acute adenovirus respiratory tract infection. Infectious adenovirus (+Ad) or HBSS (Control) was administered by intratracheal instillation into the lungs of mice (n = 3/time point). At the subsequent times indicated, mice were sacrificed and the lung epithelial lining fluid was recovered by BAL. Proinflammatory cytokine (IL-6 and TNFα) and chemoattractive chemokine (MIP-2 and MIP-1α) levels were measured in unconcentrated BAL fluid by ELISA. The entire experiment was performed twice, and representative data from one experiment are shown.