Figure 1.

Serum and PBMC derived immune marker levels in early and late pregnancy. (A) Fold change levels of cytokines derived from PBMCs in early and late pregnancy. Significant findings from the paired t-tests conducted in Table 1 are shown, outlining significant differences in PBMC cytokines from early to late pregnancy. PBMCs were stimulated with either lipopolysaccharide (LPS), resiquimod (R848), or anti-CD3/28/2. (B) Biomarker concentrations of serum samples from early and late pregnancy. Significant findings from the paired t-tests conducted in Table 1 are shown, outlining significant differences in serum cytokines from early to late pregnancy. The data is presented as mean ± SEM, with each point corresponding to the individual biomarker concentration (serum) or fold change value (PBMC) for each mother. *Significant after Benjamini Hochberg adjustment for multiple comparisons, where the threshold for significance is defined as p < q.