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. 2024 Jun 28;15:1303728. doi: 10.3389/fpsyt.2024.1303728

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Copyright © 2024 Flintoff, Alexander, Kesby and Burne

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Optimised DSST Protocol. During the testing phase, rats progressed through a series of strategy shifts. Rats had to first learn to follow a cue light and respond below the location of the visual cue (VCT), then respond only at one location (FLT). Subsequently they learnt a stimulus-response pairing during signal trials by attending to a central cue light (VCDT) and learn the reverse stimulus-response pairing during signal trials using an auditory tone ACDT. Reversals could be incorporated after FLT, VCDT or ACDT stages.