Table 5.
Distribution of Genotype and Allelic frequencies of the CHRNA5 gene between Leiomyoma and Control Population and risk analysis
|
Genotype
frequency |
Leiomyomas
N (%) |
Controls
N (%) |
p* |
OR
IC (95%) |
|---|---|---|---|---|
| GG | 61 (52.6) | 62 (33.9) | ||
| AG | 46 (39.7) | 90 (49.2) | 0.003 | - |
| AA | 9 (7.8) | 31 (16.9) | ||
| GG | 61 (52.6) | 62 (33.9) | 2.165 | |
| AG+AA | 55 (47.4) | 121 (66.1) | 0.001 | (1.345-3.484) |
| GG+AG AA |
107 (92.2) 9 (7.8) |
152 (83.1) 31 (16.9) |
0.023 | 2.425 (1.109-5.301) |
| Allele frequency | Leiomyomas N (%) | Controls N (%) | p* | OR IC (95%) |
| G | 168 (72.4) | 214 (58.5) | 1.865 | |
| A | 64 (27.6) | 152 (41.5) | <0.001 | (1.307-2.659) |
*χ2 – test